"King-Size Homer" is the seventh episode of the seventh season of the American animated television series The Simpsons. It originally aired on the Fox network in the United States on November 5, 1995. In the episode, Homer despises the nuclear plant's new exercise program and decides to attain a weight of 300 pounds (136 kg) so he can claim a disability and work from home.

The episode was written by Dan Greaney and directed by Jim Reardon. Joan Kenley makes her second of three guest appearances on The Simpsons in the episode as the voice of the telephone lady. It features cultural references to the world's heaviest twins, the 1993 film What's Eating Gilbert Grape, and the soft drink Tab.

Since airing, the episode has received positive reviews from fans and television critics, and Empire named it the best episode of the series. It acquired a Nielsen rating of 10.0 and was the third highest-rated show on the Fox network that week.